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Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies
In recent years, immunotherapies have been clinically investigated in AML and other myeloid malignancies. While most of these are focused on stimulating the adaptive immune system (including T cell checkpoint inhibitors), several key approaches targeting the innate immune system have been identified...
Autores principales: | Chao, Mark P., Takimoto, Chris H., Feng, Dong Dong, McKenna, Kelly, Gip, Phung, Liu, Jie, Volkmer, Jens-Peter, Weissman, Irving L., Majeti, Ravindra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990910/ https://www.ncbi.nlm.nih.gov/pubmed/32038992 http://dx.doi.org/10.3389/fonc.2019.01380 |
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