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Blockage of Kv1.3 regulates macrophage migration in acute liver injury by targeting δ-catenin through RhoA signaling

Background: Activation of macrophages and infiltration are key events in acute liver injury (ALI). Kv1.3 plays an important role in regulating immunologic functions of macrophages and is extensively recognized as a potential ion channel for immunological diseases. Objective: We hypothesized that blo...

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Detalles Bibliográficos
Autores principales: Wu, Baoming, Liu, Jun-da, Bian, Erbao, Hu, Wei, Huang, Cheng, Meng, Xiaoming, Zhang, Lei, Lv, Xiongwen, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990916/
https://www.ncbi.nlm.nih.gov/pubmed/32025214
http://dx.doi.org/10.7150/ijbs.38950