The Role of Akt2 in the Protective Effect of Fenofibrate against Diabetic Nephropathy

Fenofibrate (FF) protects against diabetic nephropathy (DN) in type 1 diabetic (T1D) mice by upregulating the expression of fibroblast growth factor 21 (FGF21), leading to the activation of the Akt-mediated Nrf2 antioxidant pathways. Here, we examined which isoforms of Akt contribute to FF activatio...

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Detalles Bibliográficos
Autores principales: Cheng, Yanli, Zhang, Xiaoyu, Ma, Fuzhe, Sun, Weixia, Wang, Wanning, Yu, Jinyu, Shi, Yue, Cai, Lu, Xu, Zhonggao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990917/
https://www.ncbi.nlm.nih.gov/pubmed/32025205
http://dx.doi.org/10.7150/ijbs.40643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990917/
https://www.ncbi.nlm.nih.gov/pubmed/32025205
http://dx.doi.org/10.7150/ijbs.40643

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