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The Role of Akt2 in the Protective Effect of Fenofibrate against Diabetic Nephropathy
Fenofibrate (FF) protects against diabetic nephropathy (DN) in type 1 diabetic (T1D) mice by upregulating the expression of fibroblast growth factor 21 (FGF21), leading to the activation of the Akt-mediated Nrf2 antioxidant pathways. Here, we examined which isoforms of Akt contribute to FF activatio...
Autores principales: | Cheng, Yanli, Zhang, Xiaoyu, Ma, Fuzhe, Sun, Weixia, Wang, Wanning, Yu, Jinyu, Shi, Yue, Cai, Lu, Xu, Zhonggao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990917/ https://www.ncbi.nlm.nih.gov/pubmed/32025205 http://dx.doi.org/10.7150/ijbs.40643 |
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