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Inhibition of PERK Signaling Prevents Against Glucocorticoid-induced Endotheliocyte Apoptosis and Osteonecrosis of the Femoral Head

Vascular injury is considered an important pathological process during glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH). In this study, we tried to investigate whether the endoplasmic reticulum (ER) stress is triggered in the GC-induced endotheliocyte (EC) apoptosis and ONFH. The...

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Detalles Bibliográficos
Autores principales: Gao, Yanchun, Zhu, Hongyi, Wang, Qiyang, Feng, Yong, Zhang, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990927/
https://www.ncbi.nlm.nih.gov/pubmed/32025204
http://dx.doi.org/10.7150/ijbs.35256