Exosomes transmit T790M mutation‐induced resistance in EGFR‐mutant NSCLC by activating PI3K/AKT signalling pathway

Emerging evidence has shown that exosomes derived from drug‐resistant tumour cells are able to horizontally transmit drug‐resistant phenotype to sensitive cells. However, whether exosomes shed by EGFR T790M‐mutant–resistant NSCLC cells could transfer drug resistance to sensitive cells has not been i...

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Detalles Bibliográficos
Autores principales: Liu, Xiaozhen, Jiang, Tao, Li, Xuefei, Zhao, Chao, Li, Jiayu, Zhou, Fei, Zhang, Limin, Zhao, Sha, Jia, Yijun, Shi, Jinpeng, Gao, Guanghui, Li, Wei, Zhao, Jing, Chen, Xiaoxia, Su, Chunxia, Ren, Shengxiang, Zhou, Caicun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991626/
https://www.ncbi.nlm.nih.gov/pubmed/31894895
http://dx.doi.org/10.1111/jcmm.14838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991626/
https://www.ncbi.nlm.nih.gov/pubmed/31894895
http://dx.doi.org/10.1111/jcmm.14838

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