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PNPLA3 I148M mediates the regulatory effect of NF‐kB on inflammation in PA‐treated HepG2 cells

Both PNPLA3 I148M and hepatic inflammation are associated with nonalcoholic fatty liver disease (NAFLD) progression. This study aimed to elucidate whether PNPLA3 I148M is involved in NF‐kB‐related inflammation regulation in NAFLD. HepG2 cells homozygous for the PNPLA3 I148M mutation were used. The h...

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Detalles Bibliográficos
Autores principales: Yuan, Shuhua, Liu, Hongxia, Yuan, Ding, Xu, Jing, Chen, Yunzhi, Xu, Xiao, Xu, Fen, Liang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991629/
https://www.ncbi.nlm.nih.gov/pubmed/31793207
http://dx.doi.org/10.1111/jcmm.14839