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Up‐regulation of HDACs, a harbinger of uraemic endothelial dysfunction, is prevented by defibrotide
Endothelial dysfunction is an earlier contributor to the development of atherosclerosis in chronic kidney disease (CKD), in which the role of epigenetic triggers cannot be ruled out. Endothelial protective strategies, such as defibrotide (DF), may be useful in this scenario. We evaluated changes ind...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991634/ https://www.ncbi.nlm.nih.gov/pubmed/31782253 http://dx.doi.org/10.1111/jcmm.14865 |