Cargando…

Metabolic changes during malignant transformation in primary cells of oral lichen planus: Succinate accumulation and tumour suppression

Oral squamous cell carcinoma (OSCC) is usually diagnosed at late stages, which leads to high morbidity. There are evidence that chronic inflammation (eg oral lichen planus [OLP]) was a risk factor of OSCC, but often misdiagnosed or ignored until invasion and metastasis. By applying precision medicin...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Qiaozhen, Sun, Hongying, Wang, Xiaxia, Yu, Xuedi, Zhang, Jie, Guo, Bin, Hexige, Saiyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991640/
https://www.ncbi.nlm.nih.gov/pubmed/31793175
http://dx.doi.org/10.1111/jcmm.14376