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Neutrophil extracellular traps activate lung fibroblast to induce polymyositis‐related interstitial lung diseases via TLR9‐miR‐7‐Smad2 pathway

Excessive neutrophil extracellular trap (NET) formation may contribute to polymyositis (PM)‐associated interstitial lung diseases (ILD), but the underlying mechanism is not fully revealed. In this study, we found that NET accelerated the progression of ILD and promoted pulmonary fibrosis (PF) in viv...

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Detalles Bibliográficos
Autores principales: Zhang, Sigong, Jia, Xueqin, Zhang, Qiuyue, Zhang, Li, Yang, Jing, Hu, Caihong, Shi, Junnian, Jiang, Xiao, Lu, Jinyue, Shen, Haili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991674/
https://www.ncbi.nlm.nih.gov/pubmed/31821687
http://dx.doi.org/10.1111/jcmm.14858