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PRMT5 promotes epithelial‐mesenchymal transition via EGFR‐β‐catenin axis in pancreatic cancer cells

Protein arginine methyltransferase 5 (PRMT5) has been implicated in the development and progression of human cancers. However, few studies reveal its role in epithelial‐mesenchymal transition (EMT) of pancreatic cancer cells. In this study, we find that PRMT5 is up‐regulated in pancreatic cancer, an...

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Detalles Bibliográficos
Autores principales: Ge, Lu, Wang, Huizhi, Xu, Xiao, Zhou, Zhengrong, He, Junbo, Peng, Wanxin, Du, Fengyi, Zhang, Youli, Gong, Aihua, Xu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991680/
https://www.ncbi.nlm.nih.gov/pubmed/31851779
http://dx.doi.org/10.1111/jcmm.14894