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Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model

Glioblastoma is an aggressive brain tumour found in adults, and the therapeutic approaches available have not significantly increased patient survival. Recently, we discovered that ELTD1, an angiogenic biomarker, is highly expressed in human gliomas. Polyclonal anti‐ELTD1 treatments were effective i...

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Detalles Bibliográficos
Autores principales: Zalles, Michelle, Smith, Nataliya, Ziegler, Jadith, Saunders, Debra, Remerowski, Shannon, Thomas, Lincy, Gulej, Rafal, Mamedova, Nadya, Lerner, Megan, Fung, Kar‐Ming, Chung, Junho, Hwang, Kyusang, Jin, Junyeong, Wiley, Graham, Brown, Chase, Battiste, James, Wren, Jonathan D., Towner, Rheal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991683/
https://www.ncbi.nlm.nih.gov/pubmed/31863639
http://dx.doi.org/10.1111/jcmm.14867