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Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model
Glioblastoma is an aggressive brain tumour found in adults, and the therapeutic approaches available have not significantly increased patient survival. Recently, we discovered that ELTD1, an angiogenic biomarker, is highly expressed in human gliomas. Polyclonal anti‐ELTD1 treatments were effective i...
Autores principales: | Zalles, Michelle, Smith, Nataliya, Ziegler, Jadith, Saunders, Debra, Remerowski, Shannon, Thomas, Lincy, Gulej, Rafal, Mamedova, Nadya, Lerner, Megan, Fung, Kar‐Ming, Chung, Junho, Hwang, Kyusang, Jin, Junyeong, Wiley, Graham, Brown, Chase, Battiste, James, Wren, Jonathan D., Towner, Rheal A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991683/ https://www.ncbi.nlm.nih.gov/pubmed/31863639 http://dx.doi.org/10.1111/jcmm.14867 |
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