Tks5 SH3 domains exhibit differential effects on invadopodia development

The Src substrate Tks5 helps scaffold matrix-remodeling invadopodia in invasive cancer cells. Focus was directed here on how the five SH3 domains of Tks5 impact that activity. Mutations designed to inhibit protein-protein interactions were created in the individual SH3 domains of Tks5, and the const...

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Detalles Bibliográficos
Autores principales: Daly, Christina, Logan, Brewer, Breeyear, Joseph, Whitaker, Kelley, Ahmed, Maryam, Seals, Darren F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991978/
https://www.ncbi.nlm.nih.gov/pubmed/31999741
http://dx.doi.org/10.1371/journal.pone.0227855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991978/
https://www.ncbi.nlm.nih.gov/pubmed/31999741
http://dx.doi.org/10.1371/journal.pone.0227855

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