Regulation of the ER Stress Response by the Ion Channel Activity of the Infectious Bronchitis Coronavirus Envelope Protein Modulates Virion Release, Apoptosis, Viral Fitness, and Pathogenesis

Coronavirus (CoV) envelope (E) protein is a small structural protein critical for virion morphogenesis and release. The recently characterized E protein ion channel activity (EIC) has also been implicated in modulating viral pathogenesis. In this study, we used infectious bronchitis coronavirus (IBV...

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Detalles Bibliográficos
Autores principales: Li, Shumin, Yuan, Lixia, Dai, Guo, Chen, Rui Ai, Liu, Ding Xiang, Fung, To Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992538/
https://www.ncbi.nlm.nih.gov/pubmed/32038520
http://dx.doi.org/10.3389/fmicb.2019.03022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992538/
https://www.ncbi.nlm.nih.gov/pubmed/32038520
http://dx.doi.org/10.3389/fmicb.2019.03022

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