An Update on the Structure of hERG

The human voltage-sensitive K(+) channel hERG plays a fundamental role in cardiac action potential repolarization, effectively controlling the QT interval of the electrocardiogram. Inherited loss- or gain-of-function mutations in hERG can result in dangerous “long” (LQTS) or “short” QT syndromes (SQ...

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Detalles Bibliográficos
Autores principales: Butler, Andrew, Helliwell, Matthew V., Zhang, Yihong, Hancox, Jules C., Dempsey, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992539/
https://www.ncbi.nlm.nih.gov/pubmed/32038248
http://dx.doi.org/10.3389/fphar.2019.01572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992539/
https://www.ncbi.nlm.nih.gov/pubmed/32038248
http://dx.doi.org/10.3389/fphar.2019.01572

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