A Single Step in vitro Bioassay Mimicking TLR4-LPS Pathway and the Role of MD2 and CD14 Coreceptors

Acute systemic Gram-negative bacterial infections are accompanied by release of lipopolysaccharide (LPS) endotoxins into the bloodstream and an innate immune host response via the well-known toll like receptor 4 (TLR4) pathway. In this, LPS associates non-covalently with TLR4 to form an activated he...

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Detalles Bibliográficos
Autores principales: Jagtap, Pramod, Prasad, Puja, Pateria, Abhishek, Deshmukh, Sachin D., Gupta, Shalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992608/
https://www.ncbi.nlm.nih.gov/pubmed/32038655
http://dx.doi.org/10.3389/fimmu.2020.00005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992608/
https://www.ncbi.nlm.nih.gov/pubmed/32038655
http://dx.doi.org/10.3389/fimmu.2020.00005

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