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Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

Activation of receptor tyrosine kinase (RTK) protein is frequently observed in malignant progression of gliomas. In this study, the crosstalk activation of epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition factor (MET) signaling pathways is demonstrated to contribute to t...

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Detalles Bibliográficos
Autores principales: Meng, Xiangqi, Zhao, Yu, Han, Bo, Zha, Caijun, Zhang, Yangong, Li, Ziwei, Wu, Pengfei, Qi, Tengfei, Jiang, Chuanlu, Liu, Yang, Cai, Jinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992617/
https://www.ncbi.nlm.nih.gov/pubmed/32001707
http://dx.doi.org/10.1038/s41467-019-14036-x