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Plasmid-mediated metronidazole resistance in Clostridioides difficile

Metronidazole was until recently used as a first-line treatment for potentially life-threatening Clostridioides difficile (CD) infection. Although cases of metronidazole resistance have been documented, no clear mechanism for metronidazole resistance or a role for plasmids in antimicrobial resistanc...

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Detalles Bibliográficos
Autores principales: Boekhoud, Ilse M., Hornung, Bastian V. H., Sevilla, Eloisa, Harmanus, Céline, Bos-Sanders, Ingrid M. J. G., Terveer, Elisabeth M., Bolea, Rosa, Corver, Jeroen, Kuijper, Ed J., Smits, Wiep Klaas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992631/
https://www.ncbi.nlm.nih.gov/pubmed/32001686
http://dx.doi.org/10.1038/s41467-020-14382-1