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PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer

PIM kinases have been shown to play a role in prostate cancer development and progression, as well as in some of the hallmarks of cancer, especially proliferation and apoptosis. Their upregulation in prostate cancer has been correlated with decreased patient overall survival and therapy resistance....

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Detalles Bibliográficos
Autores principales: Luszczak, Sabina, Kumar, Christopher, Sathyadevan, Vignesh Krishna, Simpson, Benjamin S., Gately, Kathy A., Whitaker, Hayley C., Heavey, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992635/
https://www.ncbi.nlm.nih.gov/pubmed/32296034
http://dx.doi.org/10.1038/s41392-020-0109-y