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Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice
Apoptosis inducing factor (AIF) has been shown to be a major contributor to neuron loss in the immature brain after hypoxia-ischemia (HI). Indeed, mice bearing a hypomorphic mutation causing reduced AIF expression are protected against neonatal HI. To further investigate the possible molecular mecha...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992638/ https://www.ncbi.nlm.nih.gov/pubmed/32001673 http://dx.doi.org/10.1038/s41419-020-2280-z |