Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice

Apoptosis inducing factor (AIF) has been shown to be a major contributor to neuron loss in the immature brain after hypoxia-ischemia (HI). Indeed, mice bearing a hypomorphic mutation causing reduced AIF expression are protected against neonatal HI. To further investigate the possible molecular mecha...

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Detalles Bibliográficos
Autores principales: Li, Tao, Li, Kenan, Zhang, Shan, Wang, Yafeng, Xu, Yiran, Cronin, Shane J. F., Sun, Yanyan, Zhang, Yaodong, Xie, Cuicui, Rodriguez, Juan, Zhou, Kai, Hagberg, Henrik, Mallard, Carina, Wang, Xiaoyang, Penninger, Josef M., Kroemer, Guido, Blomgren, Klas, Zhu, Changlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992638/
https://www.ncbi.nlm.nih.gov/pubmed/32001673
http://dx.doi.org/10.1038/s41419-020-2280-z

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