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Systemic loss of Sarm1 protects Schwann cells from chemotoxicity by delaying axon degeneration
Protecting the nervous system from chronic effects of physical and chemical stress is a pressing clinical challenge. The obligate pro-degenerative protein Sarm1 is essential for Wallerian axon degeneration. Thus, blocking Sarm1 function is emerging as a promising neuroprotective strategy with therap...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992705/ https://www.ncbi.nlm.nih.gov/pubmed/32001778 http://dx.doi.org/10.1038/s42003-020-0776-9 |