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Analysis of the polycystin complex (PCC) in human urinary exosome–like vesicles (ELVs)

The polycystin–1 (PC1), polycystin–2 (PC2) and fibrocystin proteins, the respective products of the PKD1, PKD2 and PKHD1 genes, are abundant in urinary exosome–like vesicles (ELVs) where they form the polycystin complex (PCC). ELVs are 100 nm diameter membrane vesicles shed into the urine by the cel...

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Detalles Bibliográficos
Autores principales: Lea, Wendy A., McGreal, Kerri, Sharma, Madhulika, Parnell, Stephen C., Zelenchuk, Lesya, Charlesworth, M. Cristine, Madden, Benjamin J., Johnson, Kenneth L., McCormick, Daniel J., Hogan, Marie C., Ward, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992733/
https://www.ncbi.nlm.nih.gov/pubmed/32001768
http://dx.doi.org/10.1038/s41598-020-58087-3