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Two faces of bivalent domain regulate VEGFA responsiveness and angiogenesis

The bivalent domain (BD) at promoter region is an unique epigenetic feature poised for activation or repression during cell differentiation in embryonic stem cell. However, the function of BDs in already differentiated cells remains exclusive. By profiling the epigenetic landscape of endothelial cel...

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Detalles Bibliográficos
Autores principales: Chen, Jiahuan, Liang, Xiaodong, Zhang, Shasha, Wang, Shiyan, Garcia, Sara P., Yan, Pengyi, Yu, Huijing, Li, Zixuan, Liu, Li, Zhang, Fang, Wei, Weiting, Le, Huangying, Zhang, Yan, Yuan, Guo-cheng, Chen, Sun, Chen, Yingwei, Sun, Kun, Pu, William T., Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992747/
https://www.ncbi.nlm.nih.gov/pubmed/32001672
http://dx.doi.org/10.1038/s41419-020-2228-3