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Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands

The G-quadruplex (GQ) motifs are considered as potential drug-target sites for several human pathogenic viruses such as Zika, Hepatitis, Ebola, and Human Herpesviruses. The recent outbreaks of Nipah virus (NiV) in India, the highly fatal emerging zoonotic virus is a potential threat to global health...

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Detalles Bibliográficos
Autores principales: Majee, Prativa, Kumar Mishra, Subodh, Pandya, Nirali, Shankar, Uma, Pasadi, Sanjeev, Muniyappa, K., Nayak, Debasis, Kumar, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992748/
https://www.ncbi.nlm.nih.gov/pubmed/32001794
http://dx.doi.org/10.1038/s41598-020-58406-8