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PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation

The kinase Aurora B forms the chromosomal passenger complex (CPC) together with Borealin, INCENP, and Survivin to mediate chromosome condensation, the correction of erroneous spindle-kinetochore attachments, and cytokinesis. Phosphorylation of histone H3 Thr3 by Haspin kinase and of histone H2A Thr1...

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Detalles Bibliográficos
Autores principales: Kim, Seul, Kim, Nam Hyun, Park, Ji Eun, Hwang, Jee Won, Myung, Nayeon, Hwang, Ki-Tae, Kim, Young A, Jang, Chang-Young, Kim, Yong Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992762/
https://www.ncbi.nlm.nih.gov/pubmed/32001712
http://dx.doi.org/10.1038/s41467-020-14511-w