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Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein

Rabies virus (RABV) causes fatal encephalitis in more than 59,000 people yearly. Upon the bite of an infected animal, the development of clinical disease can be prevented with post-exposure prophylaxis (PEP), which includes the administration of Rabies immunoglobulin (RIG). However, the high cost an...

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Detalles Bibliográficos
Autores principales: Hellert, Jan, Buchrieser, Julian, Larrous, Florence, Minola, Andrea, de Melo, Guilherme Dias, Soriaga, Leah, England, Patrick, Haouz, Ahmed, Telenti, Amalio, Schwartz, Olivier, Corti, Davide, Bourhy, Hervé, Rey, Félix A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992781/
https://www.ncbi.nlm.nih.gov/pubmed/32001700
http://dx.doi.org/10.1038/s41467-020-14398-7