In silico studies of piperazine derivatives as potent anti-proliferative agents against PC-3 prostate cancer cell lines

Quantitative Structure Activity Relationship studies were carried out on arylpiperazine derivatives to investigate their anti-proliferate activity against prostate PC-3 cancer cell lines. The built model with statistical parameters; R(2) = 0.8483, R(2)(adj) = 0.8078, Q(2)(cv) = 0.7122 and external v...

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Detalles Bibliográficos
Autores principales: Ikwu, Fabian A., Shallangwa, Gideon A., Mamza, Paul A., Uzairu, Adamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992985/
https://www.ncbi.nlm.nih.gov/pubmed/32021936
http://dx.doi.org/10.1016/j.heliyon.2020.e03273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992985/
https://www.ncbi.nlm.nih.gov/pubmed/32021936
http://dx.doi.org/10.1016/j.heliyon.2020.e03273

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