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In silico studies of piperazine derivatives as potent anti-proliferative agents against PC-3 prostate cancer cell lines
Quantitative Structure Activity Relationship studies were carried out on arylpiperazine derivatives to investigate their anti-proliferate activity against prostate PC-3 cancer cell lines. The built model with statistical parameters; R(2) = 0.8483, R(2)(adj) = 0.8078, Q(2)(cv) = 0.7122 and external v...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992985/ https://www.ncbi.nlm.nih.gov/pubmed/32021936 http://dx.doi.org/10.1016/j.heliyon.2020.e03273 |