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Do we really know who has an MGMT methylated glioma? Results of an international survey regarding use of MGMT analyses for glioma

BACKGROUND: Glioma O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation status informs clinical decision making. Worldwide different methods and cutoff levels are used, which can lead to discordant methylation results. METHODS: We conducted an international survey to clarify which meth...

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Detalles Bibliográficos
Autores principales: Malmström, Annika, Łysiak, Małgorzata, Kristensen, Bjarne Winther, Hovey, Elizabeth, Henriksson, Roger, Söderkvist, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993038/
https://www.ncbi.nlm.nih.gov/pubmed/32025325
http://dx.doi.org/10.1093/nop/npz039