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D-4F, an ApoA-I mimetic peptide ameliorating TRPA1-mediated nocifensive behaviour in a model of neurogenic inflammation
BACKGROUND: High doses of capsaicin are recommended for the treatment of neuropathic pain. However, low doses evoke mechanical hypersensitivity. Activation of the capsaicin chemosensor transient receptor potential vanilloid 1 (TRPV1) induces neurogenic inflammation. In addition to the release of pro...
Autores principales: | Oehler, Beatrice, Kloka, Jan, Mohammadi, Milad, Ben-Kraiem, Adel, Rittner, Heike L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993174/ https://www.ncbi.nlm.nih.gov/pubmed/31996074 http://dx.doi.org/10.1177/1744806920903848 |
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