The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In vivo Performance of (89)Zr-DFO-Pertuzumab

Rationale: The overwhelming majority of radioimmunoconjugates are produced via random conjugation methods predicated on attaching bifunctional chelators to the lysines of antibodies. However, this approach inevitably produces poorly defined and heterogeneous immunoconjugates because antibodies have...

Descripción completa

Detalles Bibliográficos
Autores principales: Vivier, Delphine, Fung, Kimberly, Rodriguez, Cindy, Adumeau, Pierre, Ulaner, Gary A., Lewis, Jason S., Sharma, Sai Kiran, Zeglis, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993239/
https://www.ncbi.nlm.nih.gov/pubmed/32042334
http://dx.doi.org/10.7150/thno.39089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993239/
https://www.ncbi.nlm.nih.gov/pubmed/32042334
http://dx.doi.org/10.7150/thno.39089

Ejemplares similares