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SREBP1 siRNA enhance the docetaxel effect based on a bone-cancer dual-targeting biomimetic nanosystem against bone metastatic castration-resistant prostate cancer

Until recently, there have been limited options for patients with bone metastatic castration-resistant prostate cancer (BmCRPC) following the failure of or development of resistance to docetaxel (DTX), which is one of the frontline treatments. Sterol regulatory element-binding protein 1 (SREBP1) is...

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Detalles Bibliográficos
Autores principales: Chen, Jiyuan, Wu, Zhenjie, Ding, Weihong, Xiao, Chengwu, Zhang, Yu, Gao, Shen, Gao, Yuan, Cai, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993241/
https://www.ncbi.nlm.nih.gov/pubmed/32042326
http://dx.doi.org/10.7150/thno.40489