Spatial heterogeneity of nanomedicine investigated by multiscale imaging of the drug, the nanoparticle and the tumour environment

Genetic and phenotypic tumour heterogeneity is an important cause of therapy resistance. Moreover, non-uniform spatial drug distribution in cancer treatment may cause pseudo-resistance, meaning that a treatment is ineffective because the drug does not reach its target at sufficient concentrations. T...

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Detalles Bibliográficos
Autores principales: de Maar, Josanne Sophia, Sofias, Alexandros Marios, Porta Siegel, Tiffany, Vreeken, Rob J., Moonen, Chrit, Bos, Clemens, Deckers, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993242/
https://www.ncbi.nlm.nih.gov/pubmed/32042343
http://dx.doi.org/10.7150/thno.38625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993242/
https://www.ncbi.nlm.nih.gov/pubmed/32042343
http://dx.doi.org/10.7150/thno.38625

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