Is there a causal link between PTEN deficient tumors and immunosuppressive tumor microenvironment?

The PTEN tumor suppressor is the second most commonly inactivated gene across cancer types. While it’s role in PI3K/AKT and DNA damage pathways are clear, increasing evidences suggest that PTEN may also promote anti-tumor immunity. PTEN-deficient tumors are characterized by (i) reduced levels of cyt...

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Detalles Bibliográficos
Autores principales: Cetintas, Vildan B., Batada, Nizar N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993356/
https://www.ncbi.nlm.nih.gov/pubmed/32000794
http://dx.doi.org/10.1186/s12967-020-02219-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993356/
https://www.ncbi.nlm.nih.gov/pubmed/32000794
http://dx.doi.org/10.1186/s12967-020-02219-w

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