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Does Xpert® MTB/RIF assay give rifampicin resistance results without identified mutation? Review of cases from Addis Ababa, Ethiopia

BACKGROUND: Xpert® MTB/RIF assay is currently used in Ethiopia for the rapid diagnosis of Mycobacterium tuberculosis (MTB) and mutations that confer Rifampicin resistance. Rifampicin resistance is determined based on any mutation in the 81 bp of rpoB gene using five overlapping probes represented as...

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Detalles Bibliográficos
Autores principales: Alemu, Ayinalem, Tadesse, Mengistu, Seid, Getachew, Mollalign, Helina, Eshetu, Kirubel, Sinshaw, Waganeh, Abebaw, Yeshiwork, Amare, Misikir, Dagne, Biniyam, Diriba, Getu, Yenew, Bazezew, Getu, Melak, Zerihun, Betselot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993378/
https://www.ncbi.nlm.nih.gov/pubmed/32000702
http://dx.doi.org/10.1186/s12879-020-4817-2