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Identification and characterization of methylation-mediated transcriptional dysregulation dictate methylation roles in preeclampsia

BACKGROUND: Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy, with no robust biomarkers or effective treatments. PE increases the risk of poor outcomes for both the mother and the baby. Methylation-mediated transcriptional dysregulation motifs (methTDMs) could contribute the...

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Detalles Bibliográficos
Autores principales: Zhao, Shuyu, Lv, Nan, Li, Yan, Liu, Tianyi, Sun, Yuhong, Chu, Xiaodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993410/
https://www.ncbi.nlm.nih.gov/pubmed/32000849
http://dx.doi.org/10.1186/s40246-020-0256-9