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ALK expressed in a gastrointestinal stromal tumor harboring PDGFRA p. D842V mutation:a case report

BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most common type of adult mesenchymal neoplasms. The events that drive GIST oncogenesis are primarily KIT or PDGFRA mutations, which lead to the susceptibility of these tumors to small-molecule tyrosine kinase inhibitors such as imatinib an...

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Detalles Bibliográficos
Autores principales: Fan, Jun, Yang, Ming, Huang, Bo, Wang, Zhenkao, Luo, Danju, Zhang, Jiwei, Zhang, Peng, Shi, Heshui, Li, Yan, Nie, Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993420/
https://www.ncbi.nlm.nih.gov/pubmed/32005261
http://dx.doi.org/10.1186/s13000-020-0926-x