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ALK expressed in a gastrointestinal stromal tumor harboring PDGFRA p. D842V mutation:a case report
BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most common type of adult mesenchymal neoplasms. The events that drive GIST oncogenesis are primarily KIT or PDGFRA mutations, which lead to the susceptibility of these tumors to small-molecule tyrosine kinase inhibitors such as imatinib an...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993420/ https://www.ncbi.nlm.nih.gov/pubmed/32005261 http://dx.doi.org/10.1186/s13000-020-0926-x |