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Genome-wide methylation and transcriptome of blood neutrophils reveal the roles of DNA methylation in affecting transcription of protein-coding genes and miRNAs in E. coli-infected mastitis cows

BACKGROUND: Neutrophils are the first effectors of inflammatory response triggered by mastitis infection, and are important defense cells against pathogenic Escherichia coli (E. coli). DNA methylation, as a critical epigenetic mechanism for regulating gene function, is involved in bovine mastitis. R...

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Detalles Bibliográficos
Autores principales: Ju, Zhihua, Jiang, Qiang, Wang, Jinpeng, Wang, Xiuge, Yang, Chunhong, Sun, Yan, Zhang, Yaran, Wang, Changfa, Gao, Yaping, Wei, Xiaochao, Hou, Minghai, Huang, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993440/
https://www.ncbi.nlm.nih.gov/pubmed/32000686
http://dx.doi.org/10.1186/s12864-020-6526-z