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Evidence of multifaceted functions of codon usage in translation within the model beetle Tribolium castaneum

Synonymous codon use is non-random. Codons most used in highly transcribed genes, often called optimal codons, typically have high gene counts of matching tRNA genes (tRNA abundance) and promote accurate and/or efficient translation. Non-optimal codons, those least used in highly expressed genes, ma...

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Detalles Bibliográficos
Autores principales: Whittle, Carrie A, Kulkarni, Arpita, Extavour, Cassandra G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993815/
https://www.ncbi.nlm.nih.gov/pubmed/31922535
http://dx.doi.org/10.1093/dnares/dsz025