Loss of Imprinting in Human Placentas Is Widespread, Coordinated, and Predicts Birth Phenotypes

Genomic imprinting leads to mono-allelic expression of genes based on parent of origin. Therian mammals and angiosperms evolved this mechanism in nutritive tissues, the placenta, and endosperm, where maternal and paternal genomes are in conflict with respect to resource allocation. We used RNA-seq t...

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Detalles Bibliográficos
Autores principales: Vincenz, Claudius, Lovett, Jennie L, Wu, Weisheng, Shedden, Kerby, Strassmann, Beverly I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993844/
https://www.ncbi.nlm.nih.gov/pubmed/31639821
http://dx.doi.org/10.1093/molbev/msz226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993844/
https://www.ncbi.nlm.nih.gov/pubmed/31639821
http://dx.doi.org/10.1093/molbev/msz226

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