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Evolutionary Analyses of Base-Pairing Interactions in DNA and RNA Secondary Structures

Pairs of nucleotides within functional nucleic acid secondary structures often display evidence of coevolution that is consistent with the maintenance of base-pairing. Here, we introduce a sequence evolution model, MESSI (Modeling the Evolution of Secondary Structure Interactions), that infers coevo...

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Detalles Bibliográficos
Autores principales: Golden, Michael, Murrell, Benjamin, Martin, Darren, Pybus, Oliver G, Hein, Jotun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993869/
https://www.ncbi.nlm.nih.gov/pubmed/31665393
http://dx.doi.org/10.1093/molbev/msz243