The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6

Cholesterol synthesis is a tightly controlled pathway, with over 20 enzymes involved. Each of these enzymes can be distinctly regulated, helping to fine-tune the production of cholesterol and its functional intermediates. Several enzymes are degraded in response to increased sterol levels, whilst ot...

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Detalles Bibliográficos
Autores principales: Scott, Nicola A., Sharpe, Laura J., Capell-Hattam, Isabelle M., Gullo, Samuel J., Luu, Winnie, Brown, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cell Homeostasis & Autophagy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993871/
https://www.ncbi.nlm.nih.gov/pubmed/31904814
http://dx.doi.org/10.1042/BCJ20190647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993871/
https://www.ncbi.nlm.nih.gov/pubmed/31904814
http://dx.doi.org/10.1042/BCJ20190647

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