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Comparison of aggregate and individual participant data approaches to meta-analysis of randomised trials: An observational study

BACKGROUND: It remains unclear when standard systematic reviews and meta-analyses that rely on published aggregate data (AD) can provide robust clinical conclusions. We aimed to compare the results from a large cohort of systematic reviews and meta-analyses based on individual participant data (IPD)...

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Detalles Bibliográficos
Autores principales: Tierney, Jayne F., Fisher, David J., Burdett, Sarah, Stewart, Lesley A., Parmar, Mahesh K. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993967/
https://www.ncbi.nlm.nih.gov/pubmed/32004320
http://dx.doi.org/10.1371/journal.pmed.1003019