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Pathologic properties of SOD3 variant R213G in the cardiovascular system through the altered neutrophils function
The SOD3 variant, SOD3(R213G), results from substitution of arginine to glycine at amino acid 213 (R213G) in its heparin binding domain (HBD) and is a common genetic variant, reported to be associated with ischemic heart disease. However, little is understood about the role of SOD3(R213G) in innate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994104/ https://www.ncbi.nlm.nih.gov/pubmed/32004354 http://dx.doi.org/10.1371/journal.pone.0227449 |