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Pathologic properties of SOD3 variant R213G in the cardiovascular system through the altered neutrophils function

The SOD3 variant, SOD3(R213G), results from substitution of arginine to glycine at amino acid 213 (R213G) in its heparin binding domain (HBD) and is a common genetic variant, reported to be associated with ischemic heart disease. However, little is understood about the role of SOD3(R213G) in innate...

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Detalles Bibliográficos
Autores principales: Kwon, Myung-Ja, Lee, Kyo-Young, Ham, Won-Gug, Tak, Lee-Jung, Agrahari, Gaurav, Kim, Tae-Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994104/
https://www.ncbi.nlm.nih.gov/pubmed/32004354
http://dx.doi.org/10.1371/journal.pone.0227449