Genetic polymorphism in C3 is associated with progression in chronic kidney disease (CKD) patients with IgA nephropathy but not in other causes of CKD

OBJECTIVES: The R102G variant in complement 3 (C3) results in two allotypic variants: C3 fast (C3F) and C3 slow (C3S). C3F presents at increased frequency in patients with chronic kidney disease (CKD), our aim is to explore its role in CKD progression and mortality. METHODS: Delta (Δ) eGFR for 2038...

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Detalles Bibliográficos
Autores principales: Ibrahim, Sara T., Chinnadurai, Rajkumar, Ali, Ibrahim, Payne, Debbie, Rice, Gillian I., Newman, William G., Algohary, Eman, Adam, Ahmed G., Kalra, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994105/
https://www.ncbi.nlm.nih.gov/pubmed/32004338
http://dx.doi.org/10.1371/journal.pone.0228101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994105/
https://www.ncbi.nlm.nih.gov/pubmed/32004338
http://dx.doi.org/10.1371/journal.pone.0228101

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