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T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection

Human rhinoviruses cause the common cold and exacerbate chronic respiratory diseases. Although infection elicits neutralizing antibodies, these do not persist or cross-protect across multiple rhinovirus strains. To analyze rhinovirus-specific B cell responses in humans, we developed techniques using...

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Detalles Bibliográficos
Autores principales: Eccles, Jacob D., Turner, Ronald B., Kirk, Nicole A., Muehling, Lyndsey M., Borish, Larry, Steinke, John W., Payne, Spencer C., Wright, Paul W., Thacker, Deborah, Lahtinen, Sampo J., Lehtinen, Markus J., Heymann, Peter W., Woodfolk, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994188/
https://www.ncbi.nlm.nih.gov/pubmed/31940481
http://dx.doi.org/10.1016/j.celrep.2019.12.027