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T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection
Human rhinoviruses cause the common cold and exacerbate chronic respiratory diseases. Although infection elicits neutralizing antibodies, these do not persist or cross-protect across multiple rhinovirus strains. To analyze rhinovirus-specific B cell responses in humans, we developed techniques using...
Autores principales: | Eccles, Jacob D., Turner, Ronald B., Kirk, Nicole A., Muehling, Lyndsey M., Borish, Larry, Steinke, John W., Payne, Spencer C., Wright, Paul W., Thacker, Deborah, Lahtinen, Sampo J., Lehtinen, Markus J., Heymann, Peter W., Woodfolk, Judith A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994188/ https://www.ncbi.nlm.nih.gov/pubmed/31940481 http://dx.doi.org/10.1016/j.celrep.2019.12.027 |
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