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Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification

The effects of the immunophilins, FKBP12 and FKBP12.6, and phosphorylation on type II ryanodine receptor (RyR2) arrangement and function were examined using correlation microscopy (line scan confocal imaging of Ca(2+) sparks and dual-tilt electron tomography) and dSTORM imaging of permeabilized Wist...

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Detalles Bibliográficos
Autores principales: Asghari, Parisa, Scriven, David RL, Ng, Myles, Panwar, Pankaj, Chou, Keng C, van Petegem, Filip, Moore, Edwin DW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994221/
https://www.ncbi.nlm.nih.gov/pubmed/31916935
http://dx.doi.org/10.7554/eLife.51602